Office: Martin O-303

Phone: (864) 656-1524

Email: edimit@clemson.edu

Fax: (864) 656-5230

Phone: (864) 656-1524

Email: edimit@clemson.edu

Fax: (864) 656-5230

# Elena Dimitrova

Position:

Associate Professor

Education:

PhD in Mathematics from Virginia Polytechnic Institute and State University, 2006

MS in Mathematics from Virginia Polytechnic Institute and State University, 2003

BA in Computer Science from American University in Bulgaria, 2001

MS in Mathematics from Virginia Polytechnic Institute and State University, 2003

BA in Computer Science from American University in Bulgaria, 2001

Professional Research Interests

Systems biology

Computational algebra

Reverse-engineering methods

Polynomial maps over finite fields

Discrete models of biochemical networks

Gröbner fans of zero-dimensional ideals

Computational algebra

Reverse-engineering methods

Polynomial maps over finite fields

Discrete models of biochemical networks

Gröbner fans of zero-dimensional ideals

Chaos theory application to biology

Professional Honors and Awards

"Data selection for unique model identification," NSF (2014-2017).

AWM-NSF Travel Grant (2013).

2011 Mathematical Sciences Faculty Teaching Award, Department of Mathematical Sciences, Clemson University (2011).

“Developing discrete network models to discover transcriptional regulation of peach fruit color,” University Research Grant Committee (URGC) (2011).

Selected Publications

- Dimitrova, E.S. (2015). Molecular network control through Boolean canalization. EURASIP Journal on Bioinformatics and Systems Biology, 2015:9.
- Dimitrova, E.S., Yordanov, O.I., Matache, M.T. (2015). A difference equation for tracking perturbations in systems of Boolean nested canalyzing functions. Physical Review Letters E, 91(6), 062812.
- Le Pape, S., Dimitrova, E.S., Hannaert, P., Konovalov, A.,Volmer, R., Ron, D., Thuillier, R., Hauet, H. (2014). Polynomial algebra as a tool to identify potential therapeutic targets: an application to ischemia-reperfusion injury. FEBS Letters, 588(17), pp. 3062-7.
- Stigler, B. and Dimitrova, E.S. (2014). Data Identification and Characterization for Improving Gene Network Inference. Accepted in Bulletin of Mathematical Biology.
- Dimitrova, E.S. and Stigler, B. (2013). Inferring the Topology of Gene Regulatory Networks: An Algebraic Approach to Reverse Engineering. In “Mathematical Concepts and Methods in Modern Biology,” Eds. Hodge, T. and Robeva, R. Elsevier.
- Layne, L., Dimitrova, E.S., Macauley, M. (2012). Nested canalyzing depth and network stability. Bulletin of Mathematical Biology, 74(2), pp. 422-433.
- Dimitrova, E.S., Mitra, I., Jarrah, A.S. (2011). Probabilistic polynomial dynamical systems for reverse engineering of gene regulatory networks. EURASIP J. on Bioinformatics and Systems Biology, 2011:1, pp. 1-33.

Links