Office: Martin O-303

Phone: (864) 656-1524

Email: edimit@clemson.edu

Fax: (864) 656-5230

Phone: (864) 656-1524

Email: edimit@clemson.edu

Fax: (864) 656-5230

# Elena Dimitrova

Position:

Associate Professor

Education:

PhD in Mathematics from Virginia Polytechnic Institute and State University, 2006

MS in Mathematics from Virginia Polytechnic Institute and State University, 2003

BA in Computer Science from American University in Bulgaria, 2001

MS in Mathematics from Virginia Polytechnic Institute and State University, 2003

BA in Computer Science from American University in Bulgaria, 2001

Professional Research Interests

Systems biology

Computational algebra

Reverse-engineering methods

Polynomial maps over finite fields

Discrete models of biochemical networks

Gröbner fans of zero-dimensional ideals

Computational algebra

Reverse-engineering methods

Polynomial maps over finite fields

Discrete models of biochemical networks

Gröbner fans of zero-dimensional ideals

Chaos theory application to biology

Professional Honors and Awards

- Selection methods for algebraic design of experiments,
NSF, 2018-2020.
- Conference grant, ACSB 2015: A Conference on Algebraic
and Combinatorial Approaches in Systems Biology, NSF, 2015.
- Data selection for unique model identification, NSF,
2014-2017.
- AWM-NSF Travel Grant, 2013.
- 2011 Mathematical Sciences Faculty Teaching Award.
- Developing discrete network models to discover
transcriptional regulation of peach fruit color, University Research Grant
Committee (URGC), 2011.
- Acquisition of Large-Memory, Many-Core Compute Node for
Mathematical Science Research,” NSF, 2010-2011.

Selected Publications

- Dimitrova,
E.S. (2017). Discrete-Time Dynamical Systems. In “Handbook of Discrete and
Combinatorial Mathematics,” 2nd Ed, Ed. Douglas Shier. CRC Press.
- Dimitrova,
E.S. and Laubenbacher, R. (2017). Boolean models in immunology. In “System
Immunology: An Introduction to Modeling Methods for Scientists,” Eds. Das,
J. and Jayaprakash, C. Taylor & Francis Group.
- Dimitrova,
E.S. (2015). Molecular network control through Boolean
canalization. EURASIP Journal on Bioinformatics and Systems Biology,
2015:9.
- Dimitrova,
E.S., Yordanov, O.I., Matache, M.T. (2015). A difference equation for
tracking perturbations in systems of Boolean nested canalyzing functions.
Physical Review Letters E, 91(6), 062812.
- Le
Pape, S., Dimitrova, E.S., Hannaert, P., Konovalov, A.,Volmer, R., Ron,
D., Thuillier, R., Hauet, H. (2014). Polynomial algebra as a tool to
identify potential therapeutic targets: an application to
ischemia-reperfusion injury. FEBS Letters, 588(17), pp. 3062-7.
- Stigler,
B. and Dimitrova, E.S. (2014). Data Identification and Characterization
for Improving Gene Network Inference. Accepted in Bulletin of Mathematical
Biology.
- Dimitrova,
E.S. and Stigler, B. (2013). Inferring the Topology of Gene Regulatory
Networks: An Algebraic Approach to Reverse Engineering. In “Mathematical
Concepts and Methods in Modern Biology,” Eds. Hodge, T. and Robeva, R.
Elsevier.
- Layne,
L., Dimitrova, E.S., Macauley, M. (2012). Nested canalyzing depth and
network stability. Bulletin of Mathematical Biology, 74(2), pp. 422-433.
- Dimitrova,
E.S., Mitra, I., Jarrah, A.S. (2011). Probabilistic polynomial dynamical
systems for reverse engineering of gene regulatory networks. EURASIP J. on
Bioinformatics and Systems Biology, 2011:1, pp. 1-33.

Links